Post orgasmic illness syndrome (POIS) is defined by a period of malaise experienced post-ejaculation. The condition mostly affects men and can be organized by symptom clusters. The seven clusters are head, eyes, nose, throat, flu-like, general, and muscle. Symptoms can be debilitating and can last anywhere from seconds to days after ejaculation. The etiology of POIS is not well understood, making it challenging to treat, and due to the variety of presentations, it can be difficult to diagnose.

The purpose of this patient registry is to raise awareness of POIS and create a database of patient-reported information, including but not limited to the symptoms they have, their time to diagnosis, and treatments they have trialed. This information will help physician scientists better understand the experiences of patients with POIS and identify what facets of the disease are most prevalent. Knowing this information will guide future research on the etiology of POIS and treatment options.

Approximately 200 participants will be recruited throughout the one year duration of this study. Prospective patients with POIS will provide consent via an electronic informed consent form to be read and completed prior to completing the survey. Data from these participants will be collected using an online public questionnaire. This protocol does not involve the administration of drugs or materials between researchers and participants, nor does it involve experimental controls or placebos. This study is currently ongoing and we are at 100 patient mark and we started submitting preliminary data to different urological conferences.

Statisctal analysis support will be provided via Department of surgery research office.

American Urological Association (AUA) Annual Meeting

Sexual Medicine Society of North America (SMSNA) meeting

Regional AUA Section (North Central Section meeting) meetings