Comprehensive Review on Peptides in Sports Medicine

Mentor
Aravind Athiviraham, MD
Orthopaedic Surgery and Rehabilitation Medicine

Description

This project focuses on a comprehensive review of peptide-based therapies that are relevant to sports medicine and musculoskeletal recovery. It aims to clarify the scientific evidence regarding the mechanisms, efficacy, and safety of commonly discussed peptides such as BPC-157, TB-500, and GHRPs. The review will address both experimental findings and clinically validated data to distinguish legitimate medical applications from unverified claims.

Specific Aims

To summarize the current scientific evidence on mechanisms of action and biological effects of peptide therapies used or discussed in sports medicine.

To critically evaluate the clinical efficacy and safety profiles of commonly utilized or emerging peptides.

To identify major gaps in clinical research and regulatory understanding related to peptide use in musculoskeletal recovery.

To clarify the boundary between experimental and evidence-based clinical applications.

Methods

Conduct a comprehensive literature search across PubMed, Embase, Web of Science, and Cochrane databases.

Include studies focusing on peptide-based interventions for musculoskeletal injury, tissue healing, or performance recovery.

Extract and synthesize information regarding mechanisms, efficacy, safety, and regulatory status.

Categorize evidence into preclinical, early clinical, and established clinical levels.

Prepare a narrative or scoping review manuscript following PRISMA-ScR guidelines for journal submission.

Scholarship & Discovery Tracks: Clinical Research